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universidade lusófona

Projects

Identification of emerging risks associated with food supplements, other than vitamins and minerals

International Coordinator: Aymeric DOPTER, ANSES-  L’Agence nationale de sécurité sanitaire de l'alimentation, de l'environnement et du travail 

PT- PI Maria do Céu Costa

CBIOS Team Members

Maria do Céu Costa & Leandra Vieira (Grant student)

From 2024 to 2026

Description

The PT -ASAE authority has consistently gathered and provided data on the safety of plant-based food supplements marketed in Europe and cooperated through Briefing Notes to its discussion as an issue of concern since the creation of EFSA (see Botanicals | EFSA (europa.eu)), and during the Emerging Risks Exchange Network (EREN) meeting in April 2021. Thus, it is greatly welcome the opportunity EFSA launched to a project for an outsourced activity that was developed by the SCER/KNOW Secretariat included under NEXT Programme, further endorsed at the Advisory Forum (AF) in March 2023.

After the kick-off meeting on 29th January, the PT -ASAE Group is actively focused on contributing to the establishment of a topic community of knowledge on food supplements, in strategic partnership, engaging with expertise for signals in nutrivigilance systems and for analyzing plant-based substances of concern.

It is also clear that the community’s role is to identify possible emerging risks without mandate to conduct risk assessment as per Regulation (EC) 178/2002 or Reg. (EC) 1925/2006.

Task 1 - Work Package 1: Establishment and moderation of Community of Knowledge on food supplements other than vitamins and minerals

Task 2 - Work Package 3: Identifying potentially hazardous food supplements, other than vitamins and minerals, containing plant-based substances with predicted toxicity in the EFSA Compendium on Botanicals

Outputs

  • Proença da Cunha, A., Costa, M.C., Pereira, A., et al. (2017) Manual de Plantas Medicinais- Bases Clínicas e Farmacológicas, ISBN: 9789725766637Edição e reimpressão: 10-2017, Editor: Dinalivro, Lisboa
  • Pereira da Silva, A., Geraldes,  M., Díaz-Lanza,  A.M., Kovacs, I.,  Costa,  M.C. (2018)Family medicine physicians' perception and attitudes of herbal substances use in greater Lisbon region. Phytomedicine. Aug 1;47:1-11. doi: 10.1016/j.phymed.2018.04.040. PMID: 30166093. https://doi.org/10.1016/j.phymed.2018.04.040
  • Costa, J.G., Vidovic, B., Saraiva, N, Costa, M.C., Del Favero, G., Marko, D., Oliveira, N.G., Fernandes, A.S. (2019) Contaminants: a dark side of food supplements? Free Radic Res. Volume 53,. https://doi.org/10.1080/10715762.2019.1636045
  • Bilia, A. R., & Costa, M. do C. (2020). Medicinal plants and their preparations in the European market: why has the harmonization failed? The cases of St. John’s wort, valerian, ginkgo, ginseng, and green tea. Phytomedicine, 153421. doi:10.1016/j.phymed.2020.153421. https://pubmed.ncbi.nlm.nih.gov/33291029/
  • Maria Lopes, Manuel A. Coimbra, Maria do Céu Costa & Fernando Ramos (2021): Food supplement vitamins, minerals, amino acids, fatty acids, phenolic and alkaloid-based substances: An overview of their interaction with drugs, Critical Reviews in Food Science and Nutrition, DOI: 10.1080/10408398.2021.1997909. https://pubmed.ncbi.nlm.nih.gov/34792411/
  • de Andrade, Sérgio Faloni, Serrador, M.G.L., Pereira da Silva, A., Tavares, R.G, Monteiro Rodrigues, L.,  Costa, M.C. (2023) Pilot study of unconventional food plant (UFP): adherence to nasturtium  (Tropaeolum majus L.) in the diet and monitoring of biometric and clinical indicators, Biomed Biopharm Res., 2022; 19(2):1-15. doi: 10.19277/bbr.19.2.295. https://www.alies.pt/BBR%20Editions/Vol-19-2-2022/bbr.19.2.295.pdf
  • Rui Aguiar and Maria do Céu Costa (2023) Active compounds and biological activities of Hypericum androsaemum L.: A review. J Pharmacogn Phytochem 12(6):48-58. DOI: 10.22271/phyto.2023.v12.i6a.14770. https://www.phytojournal.com/archives/2023/vol12issue6/PartA/12-6-19-627.pdf
  • Pereira da Silva Oliveira, A., do Céu Costa, M., & Pires Bicho, M. (2023). Use of Medicinal Plants: Interindividual Variability of Their Effects from a Genetic and Anthropological Perspective. IntechOpen. doi: 10.5772/intechopen.113841. In: Medicinal Plants - Chemical, Biochemical, and Pharmacological Approaches. https://www.intechopen.com/online-first/8873

Other participating countries

FR, NL, PT, IE, IT and BE

Participating Entities

Funding entity

EFSA.png

EFSA- European Food Safety Authority | Food supplements | EFSA (europa.eu)