Overview
Formulation Strategies & Nanosolutions Lab
The Formulation Strategies and Nanosolutions Lab develops formulations based on sustainable ingredients and biomaterials, providing optimized delivery for pharmaceutical and cosmetic applications.
Our research is focused on harnessing the benefits of biomaterials in high-performance formulations, ensuring the optimized delivery of drugs or active compounds, bridging the gap between laboratory discoveries and applications in medicines and health products.
We are particularly interested in biomaterials obtained from circular economy strategies, aligned with the United Nations Sustainable Development Goals, as the basis of active ingredients and/or functional excipients.
Formulations strategies are based on quality-by-design and nanotechnological approaches, exploring various types of lipid-based nanosystems.
We aim to deepen the understanding of sustained delivery for skin applications, with a special focus on solutions for cutaneous barrier impairment diseases and cancer.
The quality, safety, and efficacy of the innovative formulations are established through physicochemical characterization and stability studies, as well as in vitro and in vivo functional assays.
- Ionic Liquids as functional ingredients (PI: Ana Júlio)
- Nanotechnology-based formulations (PI: Catarina Pereira Leite)
- Topical and transdermal delivery (PI: Catarina Rosado)
QSONICA Q125 Sonicator
Production of nanosystems by ultra-sonication
BROOKFIELD DV3T Rheometer
Characterization of fluid viscosity at given shear rates with temperature control
LABCONCO Freezone 2.5 Freeze Dryer
Freeze drying for aqueous formulations
BROOKHAVEN NanoBrook Omni
Characterization of size, polydispersity index and zeta potential of nanoparticles
FRANZ DIFFUSION CELLS
In vitro percutaneous permeation studies with artificial membranes or human skin
- André Baby, University of São Paulo, Brazil
- Salette Reis, LAQV, REQUIMTE, Faculdade de Farmácia, Universidade do Porto, Portugal
- Kateřina Vávrová, Charles University, Faculty of Pharmacy Hradec Kralove, Czechia
- Entogreen, Ingredient Odyssey, Portugal
- SOMAÍ Pharmaceuticals, Portugal